All human children were born with 20 Baby Teeth, but after a few years, their bodies know how to replace all of them with a set of 32 entirely different, more durable Adult Teeth. How did your child body do that? No one seems to have ever studied of how that happens. Modern Medical science has focused on DNA issues for nearly everything. It seems certain that your body somehow used your unique (childhood) DNA of which you had billions of copies. An important natural time schedule appears to exist in some of your DNA. It should be possible to preserve an archive copy of your unique childhood DNA. Then, at some point in your adult life, when one or more of your adult teeth fail, why shouldn't you (somehow) be able to again use that archived DNA data to get your body to make new adult teeth (just exactly like you were able to do when you were a child)?
When adults have teeth fail, the conventional approach is to install artificial teeth, dentures, false teeth. If a copy of every child's DNA is (simply) extracted and archived, it seems that a far better approach exists. As young children, every human goes through a period of having their bodies grow natural Adult Teeth each time a Baby Tooth falls out.
Conventional biological thinking is that every base pair of the DNA of every little boy or girl is an exact copy of the same molecules of either the father or the mother.
However, this Research suggests that there must be a few prominent differences. Specifically, every little boy or girl has a capability that neither of his or her parents is currently capable of. As a young child, he or she can grow new (adult) replacement teeth. Within a few more years, he or she will no longer have that capability. This Research suggests that these changes, both ways, must be due to some (subtle) changes in his or her DNA.
Further, this Research suggests another, even more important factor, where certain DNA chromosome base pairs seem to operate on a specific time schedule, where a specific function initially may not be operational, then at a specific age, some sort of activation occurs, and then at a specific later age, that functionality ends. This research suggests that this seems to explain the "Tooth Fairy" phenomenon that all children experience, as well as a variety of Puberty experiences and even some Infant Medical immunities and other life events. This might also explain some "old age" phenomena such as loss or graying of hair or Alzheimer's and Parkinson's. If time-related effects might be discovered regarding (some) DNA induced effects, much of modern Medicine might be enhanced.
Recent Medical Research is greatly focused on Stem Cell Biology. This is great! By selectively choosing specific Genes from a person's own (childhood) DNA to inspire the person's own healthy operation, we feel that a person can naturally generate the same amino acids which it had successfully created early in life, then Medicine should even now be capable of re-growing "adult teeth" or "scalp hair" or "a perfect new breast to replace one which has developed cancer" or "a perfect new lung to replace a cancerous lung" or "an entire arm to replace one lost in an accident or illness" or many other medical maladies. All that would be needed is an entire DNA map of that person as a child, held in archive, possibly also with a tiny supply of "induced pluripotent Stem cells" which could be triggered to construct whatever bodily organ is needed.
Every little boy and girl is born with twenty baby teeth. During the first few years of his or her life, each of these baby teeth "falls out" and he or she (somehow) has the capability of replacing them with thirty two (entirely different) adult teeth. No one seems to have ever scientifically studied exactly how he or she is able to create new and entirely different adult teeth. If this capability is due to one or more DNA base pairs, then it logically seems that careful examination of his or her DNA database might provide the information for Gene Therapy for the two billion adult humans who have lost teeth, where they might grow back brand new natural adult teeth to again have a full set of excellent teeth.
We have long assumed that all of a young boy or girl's DNA base pairs are exactly identical to either those of her father or her mother. Our current Research suggests that there must be at least a few DNA base pairs which are somehow different. Our intended Research is to capture DNA database information from many little boys and girls and also from their mothers and fathers. We propose to do a simple database comparison of these three enormous file sets, so that all those DNA base pairs of the little girl's which are exact copies of either her father or mother, might be removed from the current database. I believe that such a simple comparison of his or her DNA base pairs with the DNA base pairs of his or her mother and father may identify exactly which of the little boy's or girl's genes and which DNA base pairs are different from both. This much reduced remaining database must include the possible DNA base pair or pairs which might be involved regarding the adult teeth capability.
The intended goal is to learn exactly which DNA base pairs are responsible for children's unique ability, such that we might then be able to provide DNA modifications for billions of adults, such that they might each naturally be able to grow new adult teeth after they have lost teeth.
European Molecular Biology Laboratory's Nucleotide Sequence Database,
DNA Databank of Japan
I am a Research Physicist. I believe that your wonderful achievements regarding the Human Genome Project can be greatly expanded now.
I have available four people for whom I want to obtain complete DNA data. Two are parents and the other two are their young children.
I believe that existing thinking is that every base pair of the DNA of the little girl must be exact copies of the same molecules of either the father or the mother.
However, this Research suggests that there must be a few prominent differences. Specifically, the little girl has a capability that neither of her parents is currently capable of. She can create new (adult) replacement teeth when her Baby Teeth fall out. Within a few more years, she will no longer have that capability. This Research suggests that these changes, both ways, must be due to some (subtle) changes in her DNA.
We believe that nearly all of her DNA base pairs are probably exactly identical to either those of her father or her mother, and so all those base pairs might be removed from the current database. I believe that a simple comparison of her DNA base pairs with the DNA base pairs of her mother and father may identify exactly which genes and which base pairs are different from both and so might be involved regarding the adult teeth capability.
The intended goal is to learn exactly which DNA base pairs are responsible for her unique adult teeth ability, such that we might then be able to focus on specific DNA base pairs to provide DNA modifications for billions of adults, such that they might each naturally be able to grow new adult teeth after they have lost teeth.
This would appear to be a rather simple experiment to perform, essentially just a very careful DNA record of the four individuals, followed by an equally simple computer comparison and analysis of the enormous sets of chromosome data of the four. IF this fairly simple experiment works, there may also be some similar benefits regarding Puberty changes. What if as an adult it might now be able to for her to grow possibly unique new proteins and hormones as an adults, which should never have any Immune System Rejection issues, which she already had had as a little child and as a teenager? Might it be possible to enable adults to grow lush new hair as they did as children? Might adults be able to generate complete new hormonal development as they had once done as teenagers? Might adults be able to grow strong new muscles and white blood cells and tendons or even complete organs, as they had done as children?
I propose to join forces with your Research Facility. Ideally, the four participants might travel to your Facility for extremely careful and thorough DNA analysis.
I also see future Research regarding the two children. After they are in their early twenties, any DNA changes due to Puberty should be obvious, and the exact same humans may then have DNA which has changed.
Even more importantly, say that the girl develops breast cancer (or other serious adult malady) as an adult. If her PRE-CANCER (healthy, child) DNA was then available, Medical Technology might then be able to either access some of her OWN UNIQUE child DNA or her (cryogenically stored) specific "induced pluripotent stem cells" to replace faulty (adult) cells at that time, potentially CURING the CANCER (using HER OWN UNIQUE DNA), or be able to study her own healthy child DNA and the later changed DNA database of her to learn how to do unique gene therapy for her individual body. DNA molecules cause the development of specific amino acids, which then cause the development of the necessary proteins in the creation of whatever body component that needs to be reconstructed.
We know of people who have chosen to have a second child, specifically to be a source of body components to save the life of a first child which had an incurable illness. What if that same approach might be nearly universally available, by a Doctor accessing the PRIOR DNA information from the original child?
We may find that it makes sense to take a tiny biopsy and a complete DNA archived record of all children, to forever be kept in cryogenic Biological storage and digital databases, for future Doctors to access and use to cure virtually any malady!
The technology to generate truly accurate and complete human DNA databases did not exist even ten years ago, so adults today who suffer from "black lung disease" from coal mining or from "lung cancer" due to smoking cigarettes, may not ever have the capability of using their own childhood DNA information to generate proper amino acids and protein synthesis to regenerate "brand new lungs" but that might be possible for future sufferers who have had their childhood DNA recorded in their past. Will it be possible for future Medicine to be able to use that PERSONAL DNA database to reconstruct and replace clogged blood vessels and arteries? Will it become possible to even have a person's entire heart regenerated? I wonder just what the limits might actually be! Will it some day be possible for a football player to have a perfectly new knee grown in his own body, from the exact same DNA which had grown the knee structure in the first place as a fetus and as a child? If someone such as Christopher Reeve had had this childhood archive of DNA and "induced pluripotent stem cells" created, might Doctors have been able to enable his body to recreate an entirely brand new spinal cord? There seem to be endless wonderful possibilities available from this new Methodology.
My dear friend Peter Jennings (of ABC News) died of cancer from smoking in 2006. I dream that if his childhood DNA could have been archived, Peter might still be alive and excellently healthy today.